Versatile Synthesis Tool Does Two Things at Once

Image: Maus-78, CC BY-SA 3.0

One way to synthesize complex organic molecules is to assemble them from fragments of simpler molecules using a metal catalyst. Chemists can choose from a wide variety of readily available starting materials, and a single operation can form molecules with multiple sites for making stereoisomers (mirror-image molecules). …

Published October 19, 2022, J. Am. Chem. Soc. 2022, 144, 42, 19205–19206


Dendralene Family Tree Grows Some New Branches

Adapted from Charles Darwin's "I think" sketch in his Notebook B.
Image: Stephen Johnson,
CC BY 2.0

Dendralenes highly branched molecules with multiple carbon−carbon double bonds have become versatile and economical synthetic building blocks. The first general synthetic route to [3]dendralenes, which contain 3 double bonds, was reported in 2019, and extensive research on these compounds has been published since then. …

J. Am. Chem. Soc. 2022, 144, 43, 19649–19650 (Published October 25, 2022)

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Artificial Cells Have Domains, But No Membranes

Artificial Cell Membranes

Artificial cells are synthetic agents that mimic live cells, useful as biological models or technological platforms for healthcare and bioprocessing. Like their living counterparts, artificial cells often feature internal compartments separated by membranes, which are necessary to sustain cell-like functionalities. …

JACS Spotlights, Published September 21, 2022, J. Am. Chem. Soc. 2022, 144, 38, 17317–17318